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Our comprehensive program is designed to support you through each step of the transplant process; starting with quick entry into the program. Our dedicated BMT nurse coordinator will manage the time-sensitive care coordination of critically ill children who require either an autologous or an allogeneic transplant as best chance for survival.

The first bone marrow transplant at the Cleveland Clinic was completed in , with our first pediatric transplant in This experienced team works together to provide comprehensive, individualized care for each patient. Our multidisciplinary team includes experts in the treatment of pediatric cancer as well as diseases and disorders of the blood and immune system. The team includes physicians, nurse practitioners, a nurse coordinator, social worker, psychologist, inpatient and outpatient registered nurses, nutritionists, and child life specialists.

Each week, the team reviews the list of patients currently receiving treatment and makes plans for the upcoming week and month to ensure well-coordinated care.

Bone marrow is the soft, spongy center of the bone that contains the stem cells that produce white blood cells, red blood cells, and platelets. Diseased or damaged blood cells interfere with the production of healthy blood cells and may build up in the body and invade other tissues.

What is the Pediatric Blood and Marrow Transplant Program?

A bone marrow transplant can replace unhealthy cells with healthy cells, increasing the chances of a cure. Many diseases may be treated by transplant including those listed below. We can also treat myelodysplastic syndrome, inborn errors of metabolism, and other acute and chronic leukemias, bone marrow failure syndromes, and immunodeficiencies and immune dysregulation diseases.

The immunotherapy, called CAR T-cell therapy , was approved by the Food and Drug Administration in for use in children and young adults up to age 25 who have relapsed or refractory B cell acute lymphoblastic leukemia ALL. Unlike organ transplants, blood and marrow transplants are not surgical procedures. They are more similar to blood transfusions.

The challenging part of the BMT process is managing the complications following the transplant, when the patient is extremely susceptible to infection. Depending on the transplant type, it can take several weeks for the new stem cells to begin producing enough blood cells to protect the body from germs. While waiting on new stem cells to grow into new healthy blood cells, all patients will receive aggressive monitoring and supportive care.

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This varies depending on the type of transplant and how patients are feeling and progressing after the BMT. Patients should expect frequent appointments with their transplant team for at least the first days post-transplant.

Cook Children's Hematology and Oncology - Bone Marrow Transplant

It is important to know that full recovery can take months or even years beyond that time. The combined programs received FACT re-accreditation in December of and share a common stem cell processing facility, meetings to discuss relevant patient issues, and clinical protocols, along with infrastructure and resources for clinical trial development, data collection and data monitoring.

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Pediatric Bone Marrow Transplant

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Skip Navigation. I Want To I Want to Early after the transplant, while your child is still in the hospital, we will check his or her blood each day to determine if it is growing new, healthy cells. We will also monitor your child closely for any complications related to the transplant.


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We take a team approach to caring for our young patients and their families. Besides doctors, nurse practitioners, and nurses with special expertise in transplants, our team also includes a number of specialists. We have full-time teachers on staff to help your child keep up with school. Because of the high risk of infection, children who receive a transplant will not be able to return to school right away. Whether your child is staying with us during the transplant or needs to come in on an outpatient basis, our full-time teachers provide instruction for all grades, from pre-K through high school.

We also have a dedicated team that follows children after they have fully recovered from their transplant, to ensure our survivors remain healthy throughout their lives.

The Pediatric Blood and Marrow Transplant and Cellular Therapy Program

Innovative Treatments. Why does my child need a bone marrow or stem cell transplant? What are stem cells?

Is a bone marrow transplant the same as a stem cell transplant? Is your program nationally accredited? What are the different types of transplants? What diseases are treated with a bone marrow or stem cell transplant? How do I find a donor for an allogeneic transplant? What are the different ways you can do a transplant? Will my child need chemotherapy or radiation before the transplant? How are stem cells collected? Once the stem cells are collected, when does the transplant occur? What happens after the transplant?

How will we know if the transplant is a success? Who will be caring for my child? Will my child have to miss school during the transplant process? What is the follow-up care after a stem cell transplant? Next Innovative Treatments. Life at MSK Kids.